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ube3a 抗体

ube3a 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7076104
发货至: 中国
  • 抗原 See all ube3a 抗体
    ube3a (Ubiquitin Protein Ligase E3A (ube3a))
    适用
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    小鼠, 大鼠
    宿主
    • 48
    • 3
    克隆类型
    • 47
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    多克隆
    标记
    • 28
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    This ube3a antibody is un-conjugated
    应用范围
    • 27
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    • 9
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    • 4
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    Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    大鼠
    纯化方法
    Affinity purification
    免疫原
    KLH conjugated Synthetic peptide corresponding to Mouse UBE3A
    Top Product
    Discover our top product ube3a Primary Antibody
  • 应用备注
    IHC/IF (M,R) 1:1000-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    ube3a (Ubiquitin Protein Ligase E3A (ube3a))
    别名
    UBE3A (ube3a 产品)
    背景
    UBE3A (ubiquitin-protein ligase E3A, AKA E6AP) is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the ARNTL/BMAL1, ARC, RAD23A, RAD23B, MCM7, annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B. Additionally, UBE3A may function as a cellular quality control ubiquitin ligase by helping the degradation of the cytoplasmic misfolded proteins. UBE3A also plays an important role in the regulation of the circadian clock. Defects in UBE3A are a cause of Angelman syndrome (AS).
    基因ID
    22215
    NCBI登录号
    NP_035798
    UniProt
    O08759
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway
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