TOP3B 抗体
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北京 101111
Quick Overview for TOP3B 抗体 (ABIN7075940)
抗原
See all TOP3B 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse TOP3B
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应用备注
- WB (R) 1:800-1:1500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- TOP3B (Topoisomerase (DNA) III beta (TOP3B))
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别名
- TOP3B
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背景
- This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Low expression of this gene may be related to higher survival rates in breast cancer patients. This gene has a pseudogene on chromosome 22. Alternate splicing results in multiple transcript variants.
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分子量
- 97 kDa
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基因ID
- 21976
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NCBI登录号
- NP_001313505
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UniProt
- Q9Z321
抗原
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