tau 抗体 (pSer202, pThr205)
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北京 101111
Quick Overview for tau 抗体 (pSer202, pThr205) (ABIN7075838)
抗原
See all tau 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer202, pThr205
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Affinity purification
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免疫原
- KLH conjugated Synthetic phosphopeptide corresponding to Human TAU (S202/T205)
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应用备注
- WB (H,M,R) 1:500-1:1000, IHC/IF (H,M,R) 1:600-1:1200
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限制
- 仅限研究用
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缓冲液
- , 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- tau (tau Protein)
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别名
- TAU
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背景
- Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity .The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both .Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
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分子量
- 50-80 kDa
抗原
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