tau 抗体 (pTyr18)
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北京 101111
Quick Overview for tau 抗体 (pTyr18) (ABIN2443721)
抗原
See all tau 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 12-24, pTyr18
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原理
- Phospho-Tau (tyr 18) Mouse Monoclonal Antibody (9G3)
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特异性
- The antibody recognizes the human Phospho-Tau protein at the tyrosine 18 phosphorylation site with no detectable cross-reactivity.
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纯化方法
- Protein G purified
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免疫原
- Peptide
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亚型
- IgG2a
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anti-tau Protein (pSer396) antibody
适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-tau Protein (AA 677-707), (C-Term) antibody适用: 人, 小鼠, 大鼠, Cynomolgus WB, IF, IHC (p) 宿主: 兔 Polyclonal RB2883 unconjugated
anti-tau Protein (AA 677-707) antibody适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-tau Protein antibody适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 12F4 unconjugated
anti-tau Protein (AA 681-758) antibody适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-tau Protein antibody (PerCP)适用: 人 WB, ELISA, IF, ICC, DB 宿主: 小鼠 Monoclonal 1D5 PerCP
anti-tau Protein antibody (PE)适用: 人 WB, ELISA, IF, ICC, DB 宿主: 小鼠 Monoclonal 1D5 PE
anti-tau Protein (pSer202), (pThr205) antibody (Atto 390)适用: 人 WB, ELISA, IHC, IF, ICC, DB 宿主: 兔 Monoclonal AH36 Atto 390
anti-tau Protein (pSer202), (pThr205) antibody (Atto 594)适用: 人 WB, ELISA, IHC, IF, ICC, DB 宿主: 兔 Monoclonal AH36 Atto 594
anti-tau Protein (pSer202), (pThr205) antibody (APC)适用: 人 WB, ELISA, IHC, IF, ICC, DB 宿主: 兔 Monoclonal AH36 APC
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应用备注
- WB 1:1000-1:5000,IHC 1:1000-1:5000,IF 1:2000-1:5000
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- If reconstituted with deionized water in 100 μL: WB 1:1000-1:5000, IHC 1:1000-1:5000, IF 1:2000-1:5000. Optimal dilution has to be determined by the user.
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缓冲液
- Lyophilized protein G purified in PBS pH 7.4
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.
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有效期
- 24 months
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: "Fyn kinase inhibition reduces protein aggregation, increases synapse density and improves memory in transgenic and traumatic Tauopathy." in: Acta neuropathologica communications, Vol. 8, Issue 1, pp. 96, (2020) (PubMed).
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- tau (tau Protein)
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别名
- tau
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背景
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Phosphorylated Tau
Tauopathies are a group of diverse dementias and movement disorders which have a common pathological feature in that they all display the presence of intracellular accumulation of abnormal filaments of Tau protein. While the abnormal phosphorylation of Tau on serine and threonine has been well established in the disease process, its phosphorylation on tyrosine 18 has only recently been described as present in Alzheimer's disease (AD) brain.
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UniProt
- P10636
抗原
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