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SAV1 抗体

This anti-SAV1 antibody is a 兔 多克隆 antibody detecting SAV1 in IHC 和 IF. Suitable for 小鼠 和 大鼠.
产品编号 ABIN7075505
发货至: 中国

Quick Overview for SAV1 抗体 (ABIN7075505)

抗原

See all SAV1 抗体
SAV1 (Salvador Homolog 1 (SAV1))

适用

  • 28
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
小鼠, 大鼠

宿主

  • 21
  • 6
  • 1

克隆类型

  • 25
  • 3
多克隆

标记

  • 23
  • 1
  • 1
  • 1
  • 1
  • 1
This SAV1 antibody is un-conjugated

应用范围

  • 26
  • 17
  • 9
  • 6
  • 5
  • 2
  • 1
Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 交叉反应

    大鼠

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein corresponding to Mouse SAV1
  • 应用备注

    IHC/IF (M,R) 1:200-1:1400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4, 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    SAV1 (Salvador Homolog 1 (SAV1))

    别名

    SAV1

    背景

    WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.

    基因ID

    64010

    NCBI登录号

    NP_071311

    UniProt

    Q8VEB2

    途径

    Stem Cell Maintenance
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