SUN2
适用: 人, 大鼠, 小鼠
WB, FACS, IF (cc), IF (p), IHC (p)
宿主: 兔
Monoclonal
3G4
unconjugated
应用备注
IHC/IF (H,M,R) 1:2000-1:4000/1:2000-1:4000
限制
仅限研究用
状态
Liquid
缓冲液
PBS, pH 7.4, 0.02 % sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
抗原
SUN2
(Sad1 and UNC84 Domain Containing 2 (SUN2))
别名
SUN2
背景
SUN proteins form part of the LINC complex - a protein bridge that spans the nuclear envelope linking the nucleoskeleten to the actin cytoskeleten. They are located on the inner nuclear membrane side of the complex. The LINC complex is thought to function in controlling nuclear position, contributing to mechanical resistance and the overall architecture of the cell. SUN2 can exist in a heterodimer with SUN1. Both can interact with lamins and nesprins in the nuclear envelope.