RUVBL1 抗体
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北京 101111
Quick Overview for RUVBL1 抗体 (ABIN7075488)
抗原
See all RUVBL1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse TIP49A
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应用备注
- WB (H,M) 1:500-1:1000, IHC/IF (H,R) 1:300-1:600
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- RUVBL1 (RuvB-Like 1 (E. Coli) (RUVBL1))
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别名
- TIP49A
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背景
- RUVBL1 is a member of the AAA (ATPase associated with diverse cellular activities) family of proteins that is associated with several chromatin-remodelling complexes and has important roles in transcriptional regulation, the DNA damage response, telomerase activity, snoRNP assembly, cellular transformation and cancer metastasis[PMID: 21617703]. It consists of 456 amino acids (50 kDa) and interacts with TATA-binding protein (TBP), which is a central component for transcriptional regulation by forming complexes with various transcription regulators. RUVBL1 is a component of a large nuclear protein complex, possibly the RNA polymerase II holoenzyme.
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分子量
- 55 kDa
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基因ID
- 56505
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NCBI登录号
- NP_062659
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UniProt
- P60122
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途径
- Telomere Maintenance
抗原
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