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O3FAR1 抗体

This anti-O3FAR1 antibody is a 兔 多克隆 antibody detecting O3FAR1 in IHC 和 IF. Suitable for 小鼠 和 大鼠.
产品编号 ABIN7074942
发货至: 中国

Quick Overview for O3FAR1 抗体 (ABIN7074942)

抗原

See all O3FAR1 抗体
O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))

适用

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小鼠, 大鼠

宿主

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  • 1
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克隆类型

  • 63
  • 1
多克隆

标记

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This O3FAR1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 交叉反应

    大鼠

    纯化方法

    Affinity purification

    免疫原

    KLH conjugated Synthetic peptide corresponding to Mouse GPR120
  • 应用备注

    IHC/IF (M,R) 1:1000-1:2000/1:1000-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4, 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))

    别名

    GPCR GPR120

    背景

    GPR120, a member of the rhodopsin family of G protein-coupled receptors (GPCRs), is a 377 amino acid protein which is expressed in the intestine. GPR120 is a receptor for unsaturated long-chain FFAs (free fatty acids). FFAs act as signaling molecules and are an important energy source. They also employ various physiological responses through their GPCRs. One such response occurs when dietary FFAs stimulate GPR120. This stimulation promotes the secretion of glucagon-like peptide 1 (GLP-1) in vivo and in vitro. GLP-1 belongs to the class of molecules known as the incretins, which are associated with insulin secreted from the pancreas as a result of food intake. GLP-1 also inhibits glucagon and gastric acid secretion and gastric emptying. Consequently, the role of GPR120 in the secretion of GLP-1 is critical in the treatment of diabetes.

    基因ID

    107221

    NCBI登录号

    NP_861413

    UniProt

    Q7TMA4

    途径

    Hormone Transport
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