NLRP1 抗体
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北京 101111
Quick Overview for NLRP1 抗体 (ABIN7074850)
抗原
See all NLRP1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse NLRP1
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应用备注
- IHC/IF (M,R) 1:500-1:2000/1:250-1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
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别名
- NLRP1
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背景
- NACHT, LRR and PYD domains-containing protein 1 is a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. The NLRP1 protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.
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基因ID
- 195046
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NCBI登录号
- NP_001004142
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UniProt
- Q2LKU9
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途径
- Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
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