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GDF15 抗体 (AA 221-308) (HRP)

This anti-GDF15 antibody (ABIN704570) is a Rabbit Polyclonal antibody detecting GDF15 in WB, ELISA, IHC (p), IHC (fro). Suitable for Human, Mouse, Rat.
产品编号 ABIN704570
发货至: 中国

Quick Overview for GDF15 抗体 (AA 221-308) (HRP) (ABIN704570)

抗原

See all GDF15 抗体
GDF15 (Growth Differentiation Factor 15 (GDF15))

适用

  • 116
  • 40
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  • 1
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人, 小鼠, 大鼠

宿主

  • 106
  • 26
  • 3
  • 2
  • 1

克隆类型

  • 103
  • 32
  • 2
多克隆

标记

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  • 1
  • 1
  • 1
  • 1
  • 1
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This GDF15 antibody is conjugated to HRP

应用范围

  • 112
  • 68
  • 61
  • 28
  • 23
  • 15
  • 13
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  • 6
  • 6
  • 5
  • 2
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 13
    • 12
    • 9
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    • 4
    • 2
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    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 221-308

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human GDF-15

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • Falk, Huhn, Behmenburg, Ritz-Timme, Mayer: "Biomechanical stress in myocardial infarctions: can endothelin-1 and growth differentiation factor 15 serve as immunohistochemical markers?" in: International journal of legal medicine, Vol. 132, Issue 2, pp. 509-518, (2017) (PubMed).

  • 抗原

    GDF15 (Growth Differentiation Factor 15 (GDF15))

    别名

    GDF15/MIC-1

    背景

    Synonyms: PDF, MIC1, PLAB, MIC-1, NAG-1, PTGFB, GDF-15, Growth/differentiation factor 15, Macrophage inhibitory cytokine 1, NSAID-activated gene 1 protein, NSAID-regulated gene 1 protein, NRG-1, Placental TGF-beta, Placental bone morphogenetic protein, Prostate differentiation factor, GDF15

    Background: Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues.GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53.

    基因ID

    9518

    UniProt

    Q99988

    途径

    SARS-CoV-2 Protein Interactome
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