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MPL 抗体

MPL 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7074718
发货至: 中国
  • 抗原 See all MPL 抗体
    MPL (Myeloproliferative Leukemia Virus Oncogene (MPL))
    适用
    • 57
    • 26
    • 22
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 52
    • 7
    克隆类型
    • 53
    • 6
    多克隆
    标记
    • 19
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This MPL antibody is un-conjugated
    应用范围
    • 39
    • 36
    • 16
    • 13
    • 13
    • 9
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    大鼠
    纯化方法
    Affinity purification
    免疫原
    KLH conjugated Synthetic peptide corresponding to Mouse TPOR
    Top Product
    Discover our top product MPL Primary Antibody
  • 应用备注
    IHC/IF (M,R) 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    MPL (Myeloproliferative Leukemia Virus Oncogene (MPL))
    别名
    TPOR/MPL (MPL 产品)
    别名
    C-MPL antibody, CD110 antibody, MPLV antibody, THCYT2 antibody, TPOR antibody, TPO-R antibody, c-mpl antibody, c-mpl-I antibody, c-mpl-II antibody, hlb219 antibody, MPL antibody, mpll antibody, tpor antibody, tpor.b antibody, MPL proto-oncogene, thrombopoietin receptor antibody, myeloproliferative leukemia virus oncogene antibody, MPL antibody, Mpl antibody, mpl antibody
    背景
    The protein encoded by the c-mpl gene, CD110, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs . TPO-R deficient mice were severely thrombocytopenic, emphasizing the important role of CD110 and thrombopoietin in megakaryocyte and platelet formation. Upon binding of thrombopoietin CD110 is dimerized and the JAK family of non-receptor tyrosine kinases, as well as the STAT family, the MAPK family, the adaptor protein Shc and the receptors themselves become tyrosine phosphorylated.
    基因ID
    17480
    NCBI登录号
    NP_001116421
    UniProt
    Q08351
    途径
    JAK/STAT Signaling
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