MLF1 抗体
Our Local Distributor
北京 101111
Quick Overview for MLF1 抗体 (ABIN7074712)
抗原
See all MLF1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 大鼠
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant protein corresponding to Mouse Myeloid leukemia factor 1
-
-
-
-
应用备注
- WB (M,R) 1:500-1:1000, IHC/IF (M,R) 1:1000-1:3000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
-
- MLF1 (Myeloid Leukemia Factor 1 (MLF1))
-
别名
- Myeloid leukemia factor 1
-
背景
- Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
-
分子量
- 31 kDa
-
基因ID
- 17349
-
NCBI登录号
- NP_034931
-
UniProt
- Q9QWV4
抗原
-