CD25 抗体
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北京 101111
Quick Overview for CD25 抗体 (ABIN7074349)
抗原
See all CD25 (IL2RA) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse IL2RA
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应用备注
- WB (M,R) 1: 500-1: 1000, IHC/IF (M,R) 1:200-1:1000/1:250-1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
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别名
- IL-2 Receptor alpha
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背景
- IL-2Rα(Activated T cells IL-2Rα Chain 55), also kown as membrane interleukin-2 receptor (mIL-2R) or CD25, is a protein encoded by IL2RA gene in Human. This protein is 55 kDa which is the high affinity composition of IL-2R. Few IL-2α chains will express in inactive T cells, while the expression will remarkably increase followed by IL-2 accumulation, when T cell surface receptor (TCR) is active. IL-2αchains will become soluble interleukin-2 receptor (sIL-2R) when they are detached from cell membrane into serum, and the molecular weight of sIL-2R is 45 kDa. The concentration of sIL-2R in serum can be used for a mark to measure T cells activation and IL-2Rα chains expression.
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分子量
- 45 kDa
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基因ID
- 16184
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NCBI登录号
- NP_032393
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UniProt
- P01590
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途径
- JAK/STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
抗原
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