电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CD74 抗体

This anti-CD74 antibody is a 兔 多克隆 antibody detecting CD74 in IF 和 IHC. Suitable for 小鼠 和 大鼠.
产品编号 ABIN7074245
发货至: 中国

Quick Overview for CD74 抗体 (ABIN7074245)

抗原

See all CD74 抗体
CD74 (HLA-DR-gamma (CD74))

适用

  • 207
  • 80
  • 21
  • 15
小鼠, 大鼠

宿主

  • 125
  • 104
  • 3
  • 3
  • 2

克隆类型

  • 154
  • 79
  • 3
多克隆

标记

  • 83
  • 18
  • 15
  • 9
  • 9
  • 7
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This CD74 antibody is un-conjugated

应用范围

  • 142
  • 132
  • 82
  • 56
  • 44
  • 41
  • 34
  • 26
  • 15
  • 13
  • 13
  • 13
  • 11
  • 9
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
Immunofluorescence (IF), Immunohistochemistry (IHC)
  • 交叉反应

    大鼠

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein corresponding to Mouse CD74
  • 应用备注

    IHC/IF (M,R) 1:1000-1:4000/1:500-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4, 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    CD74 (HLA-DR-gamma (CD74))

    别名

    CD74

    背景

    CD74, also known as the MHC class II associated invariant chain (Ii), is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is produced in molar excess over MHC class II and some of this is expressed by an unknown pathway on the cell surface independent of or in association with MHC class II molecules. The half life of CD74 on the cell surface is only 3 to 4 min after which it is internalized.

    基因ID

    16149

    NCBI登录号

    NP_001036070

    UniProt

    P04441

    途径

    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
You are here:
Chat with us!