HECTD1 抗体
Quick Overview for HECTD1 抗体 (ABIN7074186)
抗原
See all HECTD1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse HECTD1
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anti-HECT Domain Containing 1 (HECTD1) (AA 3-110) antibody
HECTD1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E10 unconjugated
anti-HECT Domain Containing 1 (HECTD1) antibodyHECTD1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-HECT Domain Containing 1 (HECTD1) (AA 3-110) antibodyHECTD1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-HECT Domain Containing 1 (HECTD1) (AA 3-110) antibodyHECTD1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C7 unconjugated
anti-HECT Domain Containing 1 (HECTD1) (AA 1-50) antibodyHECTD1 适用: 人, 小鼠, 大鼠, 小鸡, 犬, 非洲爪蟾, 斑马鱼 WB, IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-HECT Domain Containing 1 (HECTD1) (AA 2518-2610) antibodyHECTD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC/IF (R) 1:1000-1:2000/1:1000-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- HECTD1 (HECT Domain Containing 1 (HECTD1))
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别名
- HECTD1
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背景
- HECTD1 (E3 ubiquitin-protein ligase, which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates . Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced secretion . Negatively regulating HSP90AA1 secretion in cranial mesenchyme cells impairs their emigration and is consequently essential for the correct development of the cranial neural folds and neural tube closure.It is also involved in sporadic Parkinson's disease.
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UniProt
- Q69ZR2
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途径
- Tube Formation, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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