NEIL1 抗体
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北京 101111
Quick Overview for NEIL1 抗体 (ABIN7073820)
抗原
See all NEIL1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 大鼠
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纯化方法
- Affinity purification
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免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse NEIL1
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应用备注
- WB (M,R) 1:800-1:1600, IHC/IF (H,M,R) 1:1200-1:3000/1:300-1:600
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- NEIL1 (Endonuclease VIII-Like 1 (NEIL1))
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别名
- NEIL1
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背景
- NEIL1, also named as NEH1 and FPG1, belongs to the FPG family. It is involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. NEIL1 acts as DNA glycosylase that recognizes and removes damaged bases. It has a preference for oxidized pyrimidines, such as thymine glycol, formamidopyrimidine (Fapy) and 5-hydroxyuracil. NEIL1 has marginal activity towards 8-oxoguanine. It has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.
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分子量
- 44 kDa
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基因ID
- 72774
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NCBI登录号
- NP_082623
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UniProt
- Q8K4Q6
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途径
- DNA Damage Repair
抗原
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