CMA1 抗体
Quick Overview for CMA1 抗体 (ABIN7073506)
抗原
See all CMA1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse Chymase
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anti-Chymase 1, Mast Cell (CMA1) (Internal Region) antibody
Verified CMA1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (C-Term) antibodyCMA1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 22-247) antibodyCMA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 9-247) antibodyCMA1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 1-247) antibodyCMA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 22-247) antibodyCMA1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 22-197) antibodyCMA1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 84-118) antibodyCMA1 适用: 人 WB 宿主: 兔 Polyclonal RB53046 unconjugated
anti-Chymase 1, Mast Cell (CMA1) antibodyCMA1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 81-247) antibodyCMA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC/IF (M,R) 1:1000-1:2000/1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- CMA1 (Chymase 1, Mast Cell (CMA1))
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别名
- Mast Cell Chymase
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背景
- This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases.
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基因ID
- 17228
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NCBI登录号
- NP_034910
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UniProt
- P21844
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途径
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
抗原
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