Caspase 3 抗体 (cleaved)
Quick Overview for Caspase 3 抗体 (cleaved) (ABIN7073336)
抗原
See all Caspase 3 (CASP3) 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- cleaved
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                                            交叉反应
- 人, 大鼠
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                                            纯化方法
- Affinity purification
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                                            免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse caspase3
 
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                                            应用备注
- IHC/IF (H,M,R) 1:500-1:1000/1:500-1:1000
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C
 
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                                            : "GLUT5-mediated fructose utilization drives lung cancer growth by stimulating fatty acid synthesis and AMPK/mTORC1 signaling."    in: JCI insight, Vol. 5, Issue 3, (2021)         (PubMed).        
 : "EF24 exerts cytotoxicity against NSCLC via inducing ROS accumulation." in: Cancer cell international, Vol. 21, Issue 1, pp. 531, (2021) (PubMed).
 : "Protective effects of safranal on hypoxia/reoxygenation-induced injury in H9c2 cardiac myoblasts via the PI3K/AKT/GSK3β signaling pathway." in: Experimental and therapeutic medicine, Vol. 22, Issue 6, pp. 1400, (2021) (PubMed).
 : "Modulation of COX-2 and NADPH oxidase-4 by alpha-lipoic acid ameliorates busulfan-induced pulmonary injury in rats." in: Heliyon, Vol. 7, Issue 10, pp. e08171, (2021) (PubMed).
 : "Chrysophanol Relieves Cisplatin-Induced Nephrotoxicity via Concomitant Inhibition of Oxidative Stress, Apoptosis, and Inflammation." in: Frontiers in physiology, Vol. 12, pp. 706359, (2021) (PubMed).
 
 
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                                            : "GLUT5-mediated fructose utilization drives lung cancer growth by stimulating fatty acid synthesis and AMPK/mTORC1 signaling."    in: JCI insight, Vol. 5, Issue 3, (2021)         (PubMed).        
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    - Caspase 3 (CASP3)
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                                            别名
- Caspase-3
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                                            背景
- Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity).
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                                            基因ID
- 12367
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                                            NCBI登录号
- NP_001271338
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                                            UniProt
- P70677
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                                            途径
- Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
 抗原
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