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Caspase 3 抗体 (cleaved)

This anti-Caspase 3 antibody is a 兔 多克隆 antibody detecting Caspase 3 in IHC 和 IF. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN7073336
发货至: 中国

Quick Overview for Caspase 3 抗体 (cleaved) (ABIN7073336)

抗原

See all Caspase 3 (CASP3) 抗体
Caspase 3 (CASP3)

适用

  • 217
  • 126
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  • 6
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  • 4
  • 3
  • 3
  • 2
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  • 1
人, 小鼠, 大鼠

宿主

  • 243
  • 28
  • 3
  • 2
  • 2

克隆类型

  • 224
  • 53
多克隆

标记

  • 175
  • 21
  • 21
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  • 1
This Caspase 3 antibody is un-conjugated

应用范围

  • 214
  • 134
  • 101
  • 65
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  • 47
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  • 29
  • 27
  • 25
  • 10
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  • 1
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  • 1
Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 29
    • 16
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    • 12
    • 9
    • 9
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    • 5
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    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    cleaved

    交叉反应

    人, 大鼠

    纯化方法

    Affinity purification

    免疫原

    KLH conjugated Synthetic peptide corresponding to Mouse caspase3
  • 应用备注

    IHC/IF (H,M,R) 1:500-1:1000/1:500-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4, 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Chen, Jin, Wang, Liu, Luo, Tian, Cai, Meng, Bi, Wang, Xie, Yu, Li, Dong, Cai, Jia, Wei, Jia: "GLUT5-mediated fructose utilization drives lung cancer growth by stimulating fatty acid synthesis and AMPK/mTORC1 signaling." in: JCI insight, Vol. 5, Issue 3, (2021) (PubMed).

    Chang, Shang, Yuan, Guo, Wang: "EF24 exerts cytotoxicity against NSCLC via inducing ROS accumulation." in: Cancer cell international, Vol. 21, Issue 1, pp. 531, (2021) (PubMed).

    Wang, Zheng, Che, Han, Li, Wang, Liu, Shi, Sun: "Protective effects of safranal on hypoxia/reoxygenation-induced injury in H9c2 cardiac myoblasts via the PI3K/AKT/GSK3β signaling pathway." in: Experimental and therapeutic medicine, Vol. 22, Issue 6, pp. 1400, (2021) (PubMed).

    Elhadidy, Elmasry, Elsayed, El-Nablaway, Hamed, Elalfy, Rabei: "Modulation of COX-2 and NADPH oxidase-4 by alpha-lipoic acid ameliorates busulfan-induced pulmonary injury in rats." in: Heliyon, Vol. 7, Issue 10, pp. e08171, (2021) (PubMed).

    Ma, Xu, Huang, Gao, Zhou, Li, Zhang: "Chrysophanol Relieves Cisplatin-Induced Nephrotoxicity via Concomitant Inhibition of Oxidative Stress, Apoptosis, and Inflammation." in: Frontiers in physiology, Vol. 12, pp. 706359, (2021) (PubMed).

  • 抗原

    Caspase 3 (CASP3)

    别名

    Caspase-3

    背景

    Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity).

    基因ID

    12367

    NCBI登录号

    NP_001271338

    UniProt

    P70677

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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