Recombinant CD63 抗体
Quick Overview for Recombinant CD63 抗体 (ABIN7072636)
抗原
See all CD63 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
 - Anti-CD63 [NK-1-C3], Rabbit IgG, kappa
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特异性
 - This antibody recognizes CD63. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation and plays a role in the activation of cellular signaling cascades.
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交叉反应
 - 小鼠
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
 - Protein A affinity purified
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免疫原
 - This antibody was raised by immunizing BALB/c mice with a plasma membrane preparation of the human melanoma MeWo cells.
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亚型
 - IgG kappa
 
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应用备注
 - The antibody NK-1-C3 has been widely used for the detection and analysis of CD63 via various methods. For instance, NK-1-C3 (NK1/C3) proved successfull in labelling CD63 in multiple tissues, for example, when localizing CD63 in murine retinal pigment epithelium (RPE)/choroid tissue (Wang et al., 2009). Similarly, this antibody was used to detect CD63 on melanoma cells via immunofluorescence staining (Khazen et al., 2016).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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限制
 - 仅限研究用
 
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浓度
 - 1 mg/mL
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缓冲液
 - PBS with 0.02 % Proclin 300.
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
 
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- CD63
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别名
 - CD63
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背景
 - Granulophysin, LAMP-3, Tetraspanin-30, Tspan-30, Lysosomal-associated membrane protein 3, Melanoma-associated antigen ME491, OMA81H, Ocular melanoma-associated antigen, CD63 antigen, NK1/C3, NKI/C3, NK-1.C3, NK1C3
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UniProt
 - P08962
 
抗原
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