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Recombinant MME 抗体

The 兔 Chimeric anti-MME antibody (Clone FR4D11) (ABIN7072623) specifically detects MME in FACS, IHC 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7072623
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant MME 抗体 (ABIN7072623)

抗原

See all MME 抗体
MME (Membrane Metallo-Endopeptidase (MME))

抗体类型

Recombinant Antibody

适用

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Chimeric

标记

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This MME antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

克隆位点

FR4D11
  • 原理

    Anti-CD10 [FR4D11], Rabbit IgG, kappa

    特异性

    FR4D11 antibody recognizes CD10. It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML).

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    纯化方法

    Protein A affinity purified

    免疫原

    This antibody was raised by immunizing mice with Raji cells.

    亚型

    IgG kappa
  • 应用备注

    FR4D11 antibody can be used to identify and analyse neprilysin (CD10) via various techniques. For instance, it was utilized in the localization of neprilysin in human cerebral cortex via immunohistochemistry (Akiyama et al., 2001). This antibody was also used during a FACS analysis and phenotype characterization of Breast Cancer Stem Cells (BrCSCs) (Petrelli et al., 2015).

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    MME (Membrane Metallo-Endopeptidase (MME))

    别名

    CD10

    物质类

    Chemical

    背景

    Neprilysin, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, Enkephalinase, Neutral endopeptidase 24.11, NEP, Neutral endopeptidase, Skin fibroblast elastase, SFE, EC 3.4.24, EC 3.4.24.11, FR4D11/F3

    UniProt

    P08473

    途径

    RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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