Recombinant MARCO 抗体 (Extracellular Domain)
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Quick Overview for Recombinant MARCO 抗体 (Extracellular Domain) (ABIN7072582)
抗原
See all MARCO 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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原理
- Anti-MARCO [PLK1], Mouse IgG3, kappa
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特异性
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This antibody recognises the extracellular domain V between residues 420 and 431 in MARCO both in human and bovine samples.
Application Notes original Clone: The specificity of this antibody was confirmed in an IF experiment where the antibody stained alveolar macrophages for MACRO (Arredouani et al., 2005). Tissue samples prepared in acetone and paraformaldehyde were also successfully immunohistochemically stained (Arredouani et al., 2005, Martens et al., 2006). The antibody was also capable of weak staining of alveolar macrophages in flow cytometry (Palecanda and Kobzik, 2001). In IP experiments, the antibody immunoprecipitates MARCO from lysates obtained from COS cells transfected with human MARCO (Arredouani et al., 2005).
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纯化方法
- Protein A affinity purified
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免疫原
- The antibody was raised by immunising BALB/c mice with human alveolar macrophages (AMs) and subsequent creation of hybridomas.
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亚型
- IgG3, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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OriginalSpeciesName: Mouse
OriginalFormat: IgG3
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
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别名
- MARCO
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背景
- SCARA2, macrophage receptor MARCO, macrophage receptor with collagenous structure, scavenger receptor class A member 2, PLK-1, PLK 1
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UniProt
- Q9UEW3
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途径
- Activation of Innate immune Response
抗原
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