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Recombinant MARCO 抗体 (Extracellular Domain)

The 兔 Chimeric anti-MARCO antibody (Clone PLK1) (ABIN7072581) specifically detects MARCO in WB, IP, FACS, IF 和 IHC (fro). The antibody is reactive with 人 samples.
产品编号 ABIN7072581
发货至: 中国
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Quick Overview for Recombinant MARCO 抗体 (Extracellular Domain) (ABIN7072581)

抗原

See all MARCO 抗体
MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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Chimeric

标记

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This MARCO antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

PLK1
  • 抗原表位

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    Extracellular Domain

    原理

    Anti-MARCO [PLK1], Rabbit IgG, kappa

    特异性

    This antibody recognises the extracellular domain V between residues 420 and 431 in MARCO both in human and bovine samples.

    Application Notes original Clone: The specificity of this antibody was confirmed in an IF experiment where the antibody stained alveolar macrophages for MACRO (Arredouani et al., 2005). Tissue samples prepared in acetone and paraformaldehyde were also successfully immunohistochemically stained (Arredouani et al., 2005, Martens et al., 2006). The antibody was also capable of weak staining of alveolar macrophages in flow cytometry (Palecanda and Kobzik, 2001). In IP experiments, the antibody immunoprecipitates MARCO from lysates obtained from COS cells transfected with human MARCO (Arredouani et al., 2005).

    产品特性

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG3 format, for improved compatibility with existing reagents, assays and techniques.

    纯化方法

    Protein A affinity purified

    免疫原

    The antibody was raised by immunising BALB/c mice with human alveolar macrophages (AMs) and subsequent creation of hybridomas.

    亚型

    IgG, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    OriginalSpeciesName: Mouse

    OriginalFormat: IgG3

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

    别名

    MARCO

    背景

    SCARA2, macrophage receptor MARCO, macrophage receptor with collagenous structure, scavenger receptor class A member 2, PLK-1, PLK 1

    UniProt

    Q9UEW3

    途径

    Activation of Innate immune Response
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