Recombinant Poliovirus Receptor 抗体
Quick Overview for Recombinant Poliovirus Receptor 抗体 (ABIN7072567)
抗原
See all Poliovirus Receptor (PVR) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-CD155 [3F1], Rabbit IgG, kappa
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特异性
- This antibody is specific for murine CD155.
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产品特性
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Original Species of Ab: Rat
Original Format of Ab: IgG2a
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纯化方法
- Protein A affinity purified
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免疫原
- This antibody was raised by immunising rats with recombinant murine CD155, consisting of the entire ectodomain expressed as a HIS-tagged protein.
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亚型
- IgG kappa
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anti-Poliovirus Receptor (PVR) (AA 21-343) antibody
PVR 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6D2D6 unconjugated
anti-Poliovirus Receptor (PVR) (AA 22-255) antibodyPVR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) (AA 1-417) antibodyPVR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) (AA 56-309) antibodyPVR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) (AA 220-345) antibodyPVR 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) (Internal Region) antibodyPVR 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) (AA 21-343) antibodyPVR 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM146 unconjugated
anti-Poliovirus Receptor (PVR) (AA 314-342) antibodyPVR 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) antibodyPVR 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) antibody (APC)PVR 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal TX56 APC
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应用备注
- The binding specificity of this antibody has been confirmed both in ELISA analysis using recombinant murine CD155 (mCD155), and in flow cytometric analysis using HEK293 cells transiently expressing mCD155 (Maier et al, 2007). This antibody has been used in flow cytometry to assess mCD155 expression on lymphocytes and dendritic cells (Maier et al, 2007, Seth et al, 2011). This antibody blocks the interaction of CD155 with its ligands CD96 and CD226 (Qiu et al, 2010). When administered to WT mice, antibody-induced disruption of the CD155-CD226 interaction has been shown to cause CD226 upregulation on CD4+ T cells and CD8+ T cells (Seth et al, 2011). Administration of this antibody has also been shown to stimulate the loss of mature, memory-like CD8+ T cells from the thymus (Seth et al, 2011, Georgiev et al, 2016).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Poliovirus Receptor (PVR)
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别名
- CD155
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背景
- TAGE 3F1, Poliovirus receptor, cellular receptor for poliovirus, Pvr, Tumor-associated antigen 1, Taa1, Tage4, HVED
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UniProt
- Q8K094
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
抗原
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