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Recombinant Interleukin 17a 抗体

This anti-Interleukin 17a antibody is a 兔 Chimeric antibody detecting Interleukin 17a in ELISA 和 BP. Suitable for 小鼠.
产品编号 ABIN7072561
发货至: 中国

Quick Overview for Recombinant Interleukin 17a 抗体 (ABIN7072561)

抗原

See all Interleukin 17a (IL17A) 抗体
Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

抗体类型

Recombinant Antibody

适用

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小鼠

宿主

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克隆类型

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Chimeric

标记

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This Interleukin 17a antibody is un-conjugated

应用范围

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ELISA, Blocking Peptide (BP)

克隆位点

MM17F3
  • 原理

    Anti-IL-17A [MM17F3], Rabbit IgG, kappa

    特异性

    This antibody is highly specific for murine IL-17A, in ELISA analysis, no cross-reactivity with IL-17B, IL-17C, IL-17D, IL-17E or IL-17F was observed.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    纯化方法

    Protein A affinity purified

    免疫原

    This antibody was raised by immunising C57Bl/6 mice with IL-17A cross-linked to ovalbumin to generate a highly immunogenic complex.

    亚型

    IgG kappa
  • 应用备注

    The specificity of this antibody has been confirmed in ELISA analysis (Uyttenhove et al, 2006). This antibody inhibits IL-17A-induced IL-6 production by a Cl1D fibroblastic cell line in vitro (Uyttenhove et al, 2006). This antibody has been shown to prevent experimental autoimmune encephalomyelitis (EAE) disease development in vivo (Uyttenhove et al, 2006), as well as protecting C57Bl/6 mice from myelin oligdendrocyte glycoprotein (MOG)-induced EAE (Uyttenhove et al, 2007). Additionally, administration of this antibody inhibits collagen-induced arthritis (CIA) in IFN-γ receptor knockout mice (Kelchtermans et al, 2009).

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

    别名

    IL-17A

    背景

    Interleukin-17A, IL17A, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8

    UniProt

    Q62386
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