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Recombinant MME 抗体

This anti-MME antibody is a 兔 Chimeric antibody detecting MME in WB, IP 和 IF. Suitable for 人.
产品编号 ABIN7072451
发货至: 中国

Quick Overview for Recombinant MME 抗体 (ABIN7072451)

抗原

See all MME 抗体
MME (Membrane Metallo-Endopeptidase (MME))

抗体类型

Recombinant Antibody

适用

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克隆类型

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Chimeric

标记

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This MME antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

克隆位点

NL-1
  • 原理

    Anti-CD10 [NL-1], Rabbit IgG, kappa

    特异性

    This antibody reacts with human CD10. CD10 is a widely-expressed cell-surface metalloprotease, responsible for the cleavage of multiple peptide hormones at target tissues. CD10 is also a common marker for acute lymphocytic leukaemia.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2a

    纯化方法

    Protein A affinity purified

    免疫原

    BALB/c mice were immunised with acute lymphocytic leukaemia cells from a human leukaemia patient. Splenocytes were obtained from immunised mice and fused with MOPC-21 NS/1 myeloma cells to generate a hybridoma.

    亚型

    IgG kappa
  • 应用备注

    NL-1 was shown to react with several leukaemic cell lines using immune adherence assays (Ueda et al, 1982). These authors also confirmed that NL-1 is specific for CD10 using IP.

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    MME (Membrane Metallo-Endopeptidase (MME))

    别名

    CD10

    物质类

    Chemical

    背景

    Neprilysin, Cluster of Differentiation 10, Membrane metallo-endopeptidase, MME, Neutral endopeptidase 24.11, Neutral endopeptidase, NEP, Common acute lymphocytic leukaemia antigen, CALLA, Skin fibroblast elastase, SFE, CMT2T, SCA43, Atriopeptidase, Enkephalinase

    UniProt

    P08473

    途径

    RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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