Recombinant DARC 抗体 (N-Term)
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Quick Overview for Recombinant DARC 抗体 (N-Term) (ABIN7072437)
抗原
See all DARC 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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原理
- Anti-DARC [2C3], Rabbit IgG, kappa
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特异性
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The antibody specifically binds to the pentapeptide FEDVW of the Duffy Antigen Receptor for Chemokines (DARC). The epitope is located on the N-terminal region on the RBC surface membrane. DARC is a glycoprotein chemokine receptor and the only known receptor for Plasmodium vivax.
Application Notes original Clone: The original antibody (mouse IgG1) was generated and used successfully in ELISA, FC, and inhibition assays, blocking DARC and IL-8 binding. The antibody's epitope was also characterized (Wasniowska et al., 2002, PMID: 12164140). This antibody was successfully used in a WB (Czerwinski et al., 2007 (PMID: 17382291), Smolarek et al., 2015 (PMID: 25706384)). This antibody was successfully used to inhibit P. Vivax invasion (Russell et al., 2011 (PMID: 21768300), Urusova et al., 2019 (PMID: 31133752)).
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产品特性
- This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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纯化方法
- Protein A affinity purified
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免疫原
- CHO cells transfected with cDNA encoding the Duffy glycoprotein.
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亚型
- IgG, kappa
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anti-Duffy Blood Group, Chemokine Receptor (DARC) (N-Term) antibody
Verified DARC 适用: 人 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Duffy Blood Group, Chemokine Receptor (DARC) (AA 1-336) antibodyDARC 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Duffy Blood Group, Chemokine Receptor (DARC) (AA 71-330) antibodyDARC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Duffy Blood Group, Chemokine Receptor (DARC) (AA 1-30), (N-Term) antibodyDARC 适用: 人 WB 宿主: 兔 Polyclonal RB42735 unconjugated
anti-Duffy Blood Group, Chemokine Receptor (DARC) (AA 1-63) antibodyDARC 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Duffy Blood Group, Chemokine Receptor (DARC) (N-Term) antibody (Biotin)Verified DARC 适用: 人 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal Biotin
anti-Duffy Blood Group, Chemokine Receptor (DARC) antibody (PE)DARC 适用: 人 IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal PE
anti-Duffy Blood Group, Chemokine Receptor (DARC) (AA 1-336) antibodyDARC 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Duffy Blood Group, Chemokine Receptor (DARC) (AA 1-50) antibodyDARC 适用: 人 ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Duffy Blood Group, Chemokine Receptor (DARC) (C-Term) antibodyDARC 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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OriginalSpeciesName: Mouse
OriginalFormat: IgG1
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- DARC (Duffy Blood Group, Chemokine Receptor (DARC))
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别名
- DARC
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背景
- Fy6, Duffy Antigen Receptor for Chemokines, NaM185-2C3
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UniProt
- Q4VBN9
抗原
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