Recombinant CD276 抗体 (Extracellular Domain)
Quick Overview for Recombinant CD276 抗体 (Extracellular Domain) (ABIN7072435)
抗原
See all CD276 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
 - AA 1-242, Extracellular Domain
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原理
 - Anti-B7-H3 [MJ18], Rat IgG1, kappa
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特异性
 - This antibody binds to mouse B7-H3 and does not react with other B7-family molecules.
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产品特性
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Original Species of Ab: Rat
Original Format of Ab: IgG1
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纯化方法
 - Protein A affinity purified
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免疫原
 - This antibody was generated by immunizing Sprague Dawley rats with B7-H3-Ig, consisting of the extracellular domain (aa1-242 of mouse B7-H3) linked to the Fc portion of mouse IgG2a, emulsified in CFA (Difco). The antibody was selected by its reactivity to mouse B7-H3-transfected cells, but not to parental cells by flow cytometry.
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亚型
 - IgG1 kappa
 
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应用备注
 - This antibody has been used to detect murine B7-H3 by flow cytometry. It blocks B7-H3 signalling and can supress priming of Th2-responses and thereby the development of asthmatic responses in an ovalbumin-induced asthma model in BALB/c mice.
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限制
 - 仅限研究用
 
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浓度
 - 1 mg/mL
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缓冲液
 - PBS with 0.02 % Proclin 300.
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
 
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- CD276
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别名
 - B7-H3
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背景
 - CD276, B7H3
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UniProt
 - Q8VE98
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途径
 - Cancer Immune Checkpoints
 
抗原
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