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Recombinant CD276 抗体 (Extracellular Domain)

This 大鼠 单克隆 anti-CD276 antibody (Clone MJ18) specifically detects CD276 in FACS 和 BR. The antibody is reactive with 小鼠 samples.
产品编号 ABIN7072435
发货至: 中国
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Quick Overview for Recombinant CD276 抗体 (Extracellular Domain) (ABIN7072435)

抗原

See all CD276 抗体
CD276

抗体类型

Recombinant Antibody

适用

  • 100
  • 48
  • 15
  • 5
  • 5
  • 3
  • 2
  • 2
  • 1
小鼠

宿主

  • 62
  • 26
  • 17
  • 9
  • 1
  • 1
大鼠

克隆类型

  • 70
  • 45
  • 1
单克隆

标记

  • 59
  • 8
  • 7
  • 5
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD276 antibody is un-conjugated

应用范围

  • 64
  • 28
  • 24
  • 22
  • 17
  • 14
  • 13
  • 11
  • 8
  • 6
  • 4
  • 2
  • 1
  • 1
Flow Cytometry (FACS), Blocking Reagent (BR)

克隆位点

MJ18
  • 抗原表位

    • 15
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-242, Extracellular Domain

    原理

    Anti-B7-H3 [MJ18], Rat IgG1, kappa

    特异性

    This antibody binds to mouse B7-H3 and does not react with other B7-family molecules.

    产品特性

    Original Species of Ab: Rat

    Original Format of Ab: IgG1

    纯化方法

    Protein A affinity purified

    免疫原

    This antibody was generated by immunizing Sprague Dawley rats with B7-H3-Ig, consisting of the extracellular domain (aa1-242 of mouse B7-H3) linked to the Fc portion of mouse IgG2a, emulsified in CFA (Difco). The antibody was selected by its reactivity to mouse B7-H3-transfected cells, but not to parental cells by flow cytometry.

    亚型

    IgG1 kappa
  • 应用备注

    This antibody has been used to detect murine B7-H3 by flow cytometry. It blocks B7-H3 signalling and can supress priming of Th2-responses and thereby the development of asthmatic responses in an ovalbumin-induced asthma model in BALB/c mice.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CD276

    别名

    B7-H3

    背景

    CD276, B7H3

    UniProt

    Q8VE98

    途径

    Cancer Immune Checkpoints
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