Recombinant CD276 抗体 (Extracellular Domain)
Quick Overview for Recombinant CD276 抗体 (Extracellular Domain) (ABIN7072434)
抗原
See all CD276 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-242, Extracellular Domain
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原理
- Anti-B7-H3 [MJ18], Rabbit IgG, kappa
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特异性
- This antibody binds to mouse B7-H3 and does not react with other B7-family molecules.
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产品特性
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Original Species of Ab: Rat
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- This antibody was generated by immunizing Sprague Dawley rats with B7-H3-Ig, consisting of the extracellular domain (aa1-242 of mouse B7-H3) linked to the Fc portion of mouse IgG2a, emulsified in CFA (Difco). The antibody was selected by its reactivity to mouse B7-H3-transfected cells, but not to parental cells by flow cytometry.
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亚型
- IgG kappa
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应用备注
- This antibody has been used to detect murine B7-H3 by flow cytometry. It blocks B7-H3 signalling and can supress priming of Th2-responses and thereby the development of asthmatic responses in an ovalbumin-induced asthma model in BALB/c mice.
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD276
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别名
- B7-H3
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背景
- CD276, B7H3
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UniProt
- Q8VE98
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途径
- Cancer Immune Checkpoints
抗原
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