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Recombinant CD276 抗体 (Extracellular Domain)

This anti-CD276 antibody is a 兔 Chimeric antibody detecting CD276 in FACS 和 BR. Suitable for 小鼠.
产品编号 ABIN7072434
发货至: 中国

Quick Overview for Recombinant CD276 抗体 (Extracellular Domain) (ABIN7072434)

抗原

See all CD276 抗体
CD276

抗体类型

Recombinant Antibody

适用

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  • 1
小鼠

宿主

  • 54
  • 21
  • 7
  • 1
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克隆类型

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Chimeric

标记

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This CD276 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Blocking Reagent (BR)

克隆位点

MJ18
  • 抗原表位

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    AA 1-242, Extracellular Domain

    原理

    Anti-B7-H3 [MJ18], Rabbit IgG, kappa

    特异性

    This antibody binds to mouse B7-H3 and does not react with other B7-family molecules.

    产品特性

    Original Species of Ab: Rat

    Original Format of Ab: IgG1

    纯化方法

    Protein A affinity purified

    免疫原

    This antibody was generated by immunizing Sprague Dawley rats with B7-H3-Ig, consisting of the extracellular domain (aa1-242 of mouse B7-H3) linked to the Fc portion of mouse IgG2a, emulsified in CFA (Difco). The antibody was selected by its reactivity to mouse B7-H3-transfected cells, but not to parental cells by flow cytometry.

    亚型

    IgG kappa
  • 应用备注

    This antibody has been used to detect murine B7-H3 by flow cytometry. It blocks B7-H3 signalling and can supress priming of Th2-responses and thereby the development of asthmatic responses in an ovalbumin-induced asthma model in BALB/c mice.

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CD276

    别名

    B7-H3

    背景

    CD276, B7H3

    UniProt

    Q8VE98

    途径

    Cancer Immune Checkpoints
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