Recombinant CD81 抗体
Quick Overview for Recombinant CD81 抗体 (ABIN7072377)
抗原
See all CD81 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-CD81 [1D6], Rabbit IgG, kappa
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特异性
- This antibody is specific for human CD81, which is expressed on most tissues with the exception of red blood cells and platelets.
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交叉反应
- Chimpanzee, 山羊, 绵羊
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- This antibody was produced by immunizing mice with 5A6-aggregated OCI-LY8 B cells.
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亚型
- IgG kappa
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应用备注
- This antibody is a strong inducer of homotypic adhesion in hematolymphoid cells (Levy, 1998). This antibody also has an anti-proliferative effect, and is able to induce growth inhibition of B cell lines. Triggering of CD81 by this antibody induces a significant upregulation of the constituitive release of TNF-α by JY cells, an Eptsein-Barr virus-positive B lymphoblastoid cell line (Altomonte, 1995).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD81
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别名
- CD81
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背景
- Tetraspanin-28, TAPA-1, Target of the Antiproliferative Antibody 1, Tspan-28
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UniProt
- P60033
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途径
- Inositol Metabolic Process, Hepatitis C
抗原
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