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Recombinant Integrin beta 7 抗体

This anti-Integrin beta 7 antibody is a 大鼠 单克隆 antibody detecting Integrin beta 7 in FACS, IF 和 BR. Suitable for 人 和 小鼠.
产品编号 ABIN7072354
发货至: 中国

Quick Overview for Recombinant Integrin beta 7 抗体 (ABIN7072354)

抗原

See all Integrin beta 7 (ITGB7) 抗体
Integrin beta 7 (ITGB7)

抗体类型

Recombinant Antibody

适用

  • 69
  • 22
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 51
  • 11
  • 7
  • 4
  • 1
大鼠

克隆类型

  • 52
  • 20
  • 2
单克隆

标记

  • 36
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Integrin beta 7 antibody is un-conjugated

应用范围

  • 41
  • 22
  • 21
  • 13
  • 13
  • 7
  • 7
  • 7
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF), Blocking Reagent (BR)

克隆位点

FIB504
  • 原理

    Anti-Integrin beta-7 [FIB504], Rat IgG2a, kappa

    特异性

    FIB504 recognizes an epitope on intergin beta-7 subunit that overlaps completely with the epitope defined by Fib27 and Fib30, and also partially with the epitope defined by FIB21 and FIB22. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.

    交叉反应

    小鼠

    产品特性

    Original Species of Ab: Rat

    Original Format of Ab: IgG2a

    纯化方法

    Protein A affinity purified

    免疫原

    FIB504 was prepared by immunizing rats with TK1 cells.

    亚型

    IgG2a kappa
  • 应用备注

    FIB504 can be used for IF, FC and can block TKI cell aggregation and beta-7 intergrin-mediated cell adhesion.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    Integrin beta 7 (ITGB7)

    别名

    Integrin beta-7

    背景

    FIB-27, FIB 27, Fib-27, Fib27, Fib 27, fib27, fib-27, fib 27, Integrin b7, integrin b-7, ITGB7, Gut homing receptor beta subunit

    UniProt

    P26011

    途径

    Integrin Complex
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