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Recombinant Integrin beta 7 抗体

This anti-Integrin beta 7 antibody is a 兔 Chimeric antibody detecting Integrin beta 7 in FACS, IF 和 BR. Suitable for 人 和 小鼠.
产品编号 ABIN7072353
发货至: 中国

Quick Overview for Recombinant Integrin beta 7 抗体 (ABIN7072353)

抗原

See all Integrin beta 7 (ITGB7) 抗体
Integrin beta 7 (ITGB7)

抗体类型

Recombinant Antibody

适用

  • 69
  • 22
  • 1
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人, 小鼠

宿主

  • 50
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  • 7
  • 4
  • 1

克隆类型

  • 52
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  • 1
Chimeric

标记

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  • 2
  • 1
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This Integrin beta 7 antibody is un-conjugated

应用范围

  • 41
  • 22
  • 21
  • 13
  • 13
  • 7
  • 7
  • 7
  • 4
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Flow Cytometry (FACS), Immunofluorescence (IF), Blocking Reagent (BR)

克隆位点

FIB504
  • 原理

    Anti-Integrin beta-7 [FIB504], Rabbit IgG, kappa

    特异性

    FIB504 recognizes an epitope on intergin beta-7 subunit that overlaps completely with the epitope defined by Fib27 and Fib30, and also partially with the epitope defined by FIB21 and FIB22. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.

    交叉反应

    小鼠

    产品特性

    Original Species of Ab: Rat

    Original Format of Ab: IgG2a

    纯化方法

    Protein A affinity purified

    免疫原

    FIB504 was prepared by immunizing rats with TK1 cells.

    亚型

    IgG kappa
  • 应用备注

    FIB504 can be used for IF, FC and can block TKI cell aggregation and beta-7 intergrin-mediated cell adhesion.

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    Integrin beta 7 (ITGB7)

    别名

    Integrin beta-7

    背景

    FIB-27, FIB 27, Fib-27, Fib27, Fib 27, fib27, fib-27, fib 27, Integrin b7, integrin b-7, ITGB7, Gut homing receptor beta subunit

    UniProt

    P26011

    途径

    Integrin Complex
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