Recombinant Endoglin 抗体
Quick Overview for Recombinant Endoglin 抗体 (ABIN7072351)
抗原
See all Endoglin (ENG) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-CD105 [MJ7/18], Rabbit IgG, kappa
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特异性
- MJ7/18 binds specifically to mouse CD105. CD105 is a homodimer expressed by vascular endothelial cells. CD105 functions in adhesion and embryonic angiogenesis. CD105 is a major homodimeric glycoprotein of vascular endothelium involved in cell ahesion through integrin/RGD binding and the regulation of angiogenesis. Also acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. CD105 is also required for GDF2/BMP9 signaling through SMAD1 in endothelial cells.
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产品特性
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Original Species of Ab: Rat
Original Format of Ab: IgG2a
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纯化方法
- Protein A affinity purified
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免疫原
- MJ7/18 was prepared by immunizing rats with inflamed mouse skin tissue. The antibody was selected immunohistologically for reactivity with endothelial cells.
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亚型
- IgG kappa
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anti-Endoglin (ENG) (AA 58-110) antibody
ENG 适用: 人, 小鼠, 大鼠, 犬 WB, FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Endoglin (ENG) (AA 27-137) antibodyENG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Endoglin (ENG) (AA 26-136) antibodyENG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Endoglin (ENG) (AA 26-136) antibodyENG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Endoglin (ENG) antibodyENG 适用: 人 FACS, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Endoglin (ENG) (AA 27-226) antibodyENG 适用: 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Endoglin (ENG) (AA 601-658) antibodyENG 适用: 人, 大鼠 ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Endoglin (ENG) antibodyENG 适用: 人, 大鼠 WB, FACS, IP, MS 宿主: 小鼠 Monoclonal MEM-226 unconjugated
anti-Endoglin (ENG) antibody (APC)ENG 适用: 人, 大鼠 FACS 宿主: 小鼠 Monoclonal MEM-226 APC
anti-Endoglin (ENG) (AA 370-430) antibodyENG 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- MJ7/18 can be used for FC, WB, IP and IHC (Baluk P, et al. 2003. Am. J. Pathol. 163:1801).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Endoglin (ENG)
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别名
- CD105
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背景
- Endoglin, Cell surface MJ7/18 antigen
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UniProt
- Q63961
抗原
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