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Recombinant Discoidin Domain Receptor 1 (Extracellular Domain) 抗体

The 兔 Chimeric anti-Discoidin Domain Receptor 1 antibody (Clone 3E3) (ABIN7072320) specifically detects Discoidin Domain Receptor 1 in BP, ELISA 和 WB. The antibody is reactive with 人 samples.
产品编号 ABIN7072320
发货至: 中国
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Quick Overview for Recombinant Discoidin Domain Receptor 1 (Extracellular Domain) 抗体 (ABIN7072320)

抗原

Discoidin Domain Receptor 1

抗体类型

Recombinant Antibody

适用

宿主

  • 1

克隆类型

  • 1
Chimeric

标记

  • 1
非结合性

应用范围

Blocking Peptide (BP), ELISA, Western Blotting (WB)

克隆位点

3E3
  • 抗原表位

    Extracellular Domain

    原理

    Anti-Discoidin Domain Receptor 1 [3E3], Rabbit IgG, kappa

    特异性

    This antibody binds specifically to the extracellular domain of human DDR1.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2

    纯化方法

    Protein A affinity purified

    免疫原

    Recombinant human DDR1 extracellular domain.

    亚型

    IgG kappa
  • 应用备注

    This antibody binds to human Discoidin Domain Receptor 1, a receptor tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates the attachemnt of the cell to the extracellular matrix. This receptor is required for blastocyst implantation during pregnancy, mammary gland differentiation as well as lactation. It promotes smooth muscle cell migration as well as tumour cell invasion. The antibody acts as an antagonist.

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    Discoidin Domain Receptor 1

    背景

    DDR1

    UniProt

    Q08345
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