Recombinant Discoidin Domain Receptor 1 (Extracellular Domain) 抗体
The 小鼠 单克隆 anti-Discoidin Domain Receptor 1 antibody is suitable to detect Discoidin Domain Receptor 1 in samples from 人. It has been validated for BP, ELISA 和 WB.
产品编号 ABIN7072319
发货至:
中国
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Quick Overview for Recombinant Discoidin Domain Receptor 1 (Extracellular Domain) 抗体 (ABIN7072319)
抗原
Discoidin Domain Receptor 1
抗体类型
Recombinant Antibody
适用
人
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Blocking Peptide (BP), ELISA, Western Blotting (WB)
克隆位点
3E3
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抗原表位
- Extracellular Domain
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原理
- Anti-Discoidin Domain Receptor 1 [3E3], Mouse IgG1, kappa
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特异性
- This antibody binds specifically to the extracellular domain of human DDR1.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG2
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纯化方法
- Protein A affinity purified
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免疫原
- Recombinant human DDR1 extracellular domain.
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亚型
- IgG1 kappa
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应用备注
- This antibody binds to human Discoidin Domain Receptor 1, a receptor tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates the attachemnt of the cell to the extracellular matrix. This receptor is required for blastocyst implantation during pregnancy, mammary gland differentiation as well as lactation. It promotes smooth muscle cell migration as well as tumour cell invasion. The antibody acts as an antagonist.
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说明
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This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Discoidin Domain Receptor 1
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背景
- DDR1
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UniProt
- Q08345
抗原
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