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Recombinant Paxillin (LD4 Motif) (AA 260-278) 抗体

The 兔 Chimeric anti-Paxillin (LD4 Motif) antibody is suitable to detect Paxillin (LD4 Motif) in samples from 人. It has been validated for ELISA 和 WB.
产品编号 ABIN7072304
发货至: 中国
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Quick Overview for Recombinant Paxillin (LD4 Motif) (AA 260-278) 抗体 (ABIN7072304)

抗原

Paxillin (LD4 Motif)

抗体类型

Recombinant Antibody

适用

宿主

  • 1

克隆类型

  • 1
Chimeric

标记

  • 1
非结合性

应用范围

ELISA, Western Blotting (WB)

克隆位点

LD4 sAB
  • 抗原表位

    AA 260-278

    原理

    Anti-Paxillin (LD4 Motif) [LD4 sAB], Rabbit IgG, kappa

    特异性

    The antibody binds specifically to the LD-4 motif of human paxillin with a Kd of 6 nM.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: scFv

    纯化方法

    Protein A affinity purified

    免疫原

    Peptide corresponding to human paxillin-LD4 motif (residues 260-278) fused to MBP, peptide sequence: WGGSATRELDELMASLSD.

    亚型

    IgG kappa
  • 应用备注

    This antibody binds to the LD4-motif of human paxillin, a signal transduction adaptor protein involved in focal adhesion, with binding partners including integrins, Src, FAK or actin complexes. The antibody inhibits complex formation between paxillin and FAK. Paxillin is involved in both inside-out cell signalling and outside-to-inside cell signalling.

    说明

    This full-length, chimeric rabbit antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    Paxillin (LD4 Motif)

    背景

    PXN

    UniProt

    P49023
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