Recombinant Paxillin (LD4 Motif) (AA 260-278) 抗体
This 小鼠 单克隆 antibody specifically detects Paxillin (LD4 Motif) in ELISA 和 WB. It exhibits reactivity toward 人.
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产品编号 ABIN7072303
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for Recombinant Paxillin (LD4 Motif) (AA 260-278) 抗体 (ABIN7072303)
抗原
Paxillin (LD4 Motif)
抗体类型
Recombinant Antibody
适用
人
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB)
克隆位点
LD4 sAB
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抗原表位
- AA 260-278
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原理
- Anti-Paxillin (LD4 Motif) [LD4 sAB], Mouse IgG1, kappa
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特异性
- The antibody binds specifically to the LD-4 motif of human paxillin with a Kd of 6 nM.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: scFv
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纯化方法
- Protein A affinity purified
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免疫原
- Peptide corresponding to human paxillin-LD4 motif (residues 260-278) fused to MBP, peptide sequence: WGGSATRELDELMASLSD.
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亚型
- IgG1 kappa
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应用备注
- This antibody binds to the LD4-motif of human paxillin, a signal transduction adaptor protein involved in focal adhesion, with binding partners including integrins, Src, FAK or actin complexes. The antibody inhibits complex formation between paxillin and FAK. Paxillin is involved in both inside-out cell signalling and outside-to-inside cell signalling.
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说明
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This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Paxillin (LD4 Motif)
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背景
- PXN
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UniProt
- P49023
抗原
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