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Recombinant CD28 抗体

This anti-CD28 antibody is a 小鼠 单克隆 antibody detecting CD28 in FACS, IHC, SPR, CoSt 和 Agon. Suitable for 小鼠.
产品编号 ABIN7072236
发货至: 中国

Quick Overview for Recombinant CD28 抗体 (ABIN7072236)

抗原

See all CD28 抗体
CD28

抗体类型

Recombinant Antibody

适用

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小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD28 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Surface Plasmon Resonance (SPR), Co-Stimulation (CoSt), Agonist (Agon)

克隆位点

D665
  • 原理

    Anti-CD28 [D665], Mouse IgG1, kappa

    特异性

    This antibody binds to the laterally exposed C'D loop of CD28 and induces T cell proliferation without TCR ligation.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    纯化方法

    Protein A affinity purified

    免疫原

    The original D665 antibody was generated by immunizing mice alternately with A20 cells expressing mCD28 i.p. and with recombinant mCD28Ig s.c.

    亚型

    IgG1 kappa
  • 应用备注

    This antibody binds to mouse CD28. The original mouse IgG1 version was shown to trigger T-cell proliferation in vitro and in vivo in a TCR-independent manner and is a superagonistic antibody. This antibody does not compete with E18 (Ab00286).

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CD28

    别名

    CD28

    背景

    TP44, T-cell-specific surface glycoprotein CD28, TP44

    UniProt

    P31041

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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