Recombinant CD28 抗体
Quick Overview for Recombinant CD28 抗体 (ABIN7072236)
抗原
See all CD28 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-CD28 [D665], Mouse IgG1, kappa
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特异性
- This antibody binds to the laterally exposed C'D loop of CD28 and induces T cell proliferation without TCR ligation.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- The original D665 antibody was generated by immunizing mice alternately with A20 cells expressing mCD28 i.p. and with recombinant mCD28Ig s.c.
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亚型
- IgG1 kappa
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应用备注
- This antibody binds to mouse CD28. The original mouse IgG1 version was shown to trigger T-cell proliferation in vitro and in vivo in a TCR-independent manner and is a superagonistic antibody. This antibody does not compete with E18 (Ab00286).
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD28
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别名
- CD28
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背景
- TP44, T-cell-specific surface glycoprotein CD28, TP44
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UniProt
- P31041
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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