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Recombinant CD28 抗体

This anti-CD28 antibody is a 兔 Chimeric antibody detecting CD28 in FACS, IF, IHC, CoSt 和 Agon. Suitable for 大鼠.
产品编号 ABIN7072235
发货至: 中国

Quick Overview for Recombinant CD28 抗体 (ABIN7072235)

抗原

See all CD28 抗体
CD28

抗体类型

Recombinant Antibody

适用

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克隆类型

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Chimeric

标记

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This CD28 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Co-Stimulation (CoSt), Agonist (Agon)

克隆位点

JJ316
  • 原理

    Anti-CD28 [JJ316], Rabbit IgG, kappa

    特异性

    Recognises rat CD28 and can trigger T-cell proliferation in vitro and in vivo.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    纯化方法

    Protein A affinity purified

    免疫原

    Made by immunizing BALB/c mice with rat CD28 cDNA-transfected A20/J cells.

    亚型

    IgG kappa
  • 应用备注

    This antibody binds rat CD28 and can convey as a co-stimulatory signal. At 100-1000-fold higher concentration than required for co-stimulation JJ316 (unlike the clone JJ319 marketed by competitors (see Tacke et al. 1997)) can induce proliferation of all T-cell subsets without TCR engagement.

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CD28

    别名

    CD28

    背景

    TP44, T-cell-specific surface glycoprotein CD28

    UniProt

    P31042

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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