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Recombinant CD28 抗体

This 小鼠 单克隆 antibody specifically detects CD28 in FACS, IF, IHC, CoSt 和 Agon. It exhibits reactivity toward 大鼠.
产品编号 ABIN7072234
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant CD28 抗体 (ABIN7072234)

抗原

See all CD28 抗体
CD28

抗体类型

Recombinant Antibody

适用

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大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD28 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Co-Stimulation (CoSt), Agonist (Agon)

克隆位点

JJ316
  • 原理

    Anti-CD28 [JJ316], Mouse IgG1, kappa

    特异性

    Recognises rat CD28 and can trigger T-cell proliferation in vitro and in vivo.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    纯化方法

    Protein A affinity purified

    免疫原

    Made by immunizing BALB/c mice with rat CD28 cDNA-transfected A20/J cells.

    亚型

    IgG1 kappa
  • 应用备注

    This antibody binds rat CD28 and can convey as a co-stimulatory signal. At 100-1000-fold higher concentration than required for co-stimulation JJ316 (unlike the clone JJ319 marketed by competitors (see Tacke et al. 1997)) can induce proliferation of all T-cell subsets without TCR engagement.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CD28

    别名

    CD28

    背景

    TP44, T-cell-specific surface glycoprotein CD28

    UniProt

    P31042

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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