Recombinant CD8 alpha/lyt-2 抗体
适用: 小鼠
Dep, FACS, IHC, IHC (fro), in vivo
宿主: 兔
Chimeric
YTS 169-4
unconjugated
Recombinant Antibody
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- 抗原
- CD8 alpha/lyt-2
- 抗体类型
- Recombinant Antibody
- 适用
- 小鼠
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宿主
- 兔
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克隆类型
- Chimeric
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标记
- 非结合性
- 应用范围
- Depletion (Dep), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), In vivo Studies (in vivo)
- 原理
- Anti-CD8 alpha/Lyt-2 [YTS 169.4], Rabbit IgG, kappa
- 特异性
- This antibody recognises the murine CD8 cell surface antigen expressed by a subset of T lymphocytes.
- 产品特性
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Original Species of Ab: Rat
Original Format of Ab: IgG2b
- 纯化方法
- Protein A affinity purified
- 免疫原
- Murine CD8 (Lyt-2).
- 克隆位点
- YTS 169-4
- 亚型
- IgG kappa
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- 应用备注
- The antibody has been shown to show depleting activity in vivo. Mice have two alleles for CD8, Lyt2.1, and Lyt2.2, which are restricted to certain mouse strains. Lyt2.1, for example, is expressed in the mouse strains CBA, AKR, C3H, and DBA, whereas Lyt2.2 is expressed in the mouse strains BALB/c and C57BL/6 (B/6). YTS 169.4 was originally raised against CBA mouse thymocytes. However, there are publications in which it has been used in C57BL/6 and BALB/c mice, wherein it was used specifically as a pan-reactive Lyt2 reagent (Tavaré et al., 2014, PMID: 24390540).
- 说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques.
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % Proclin 300.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- 抗原
- CD8 alpha/lyt-2
- 背景
- Leu2, CD8, CD8A, CD8a molecule, CD8a antigen, Leu2 T-lymphocyte antigen, Lyt-2, Lyt2OKT8, p32T-cell antigen Leu2, T-cell antigen, T cell co-receptor, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2, T8 T-cell antigen
- UniProt
- P01731
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