Recombinant Bax (Active Monomer) (AA 12-24), (AA 3-16) 抗体
The 兔 Chimeric anti-Bax (Active Monomer) antibody is suitable to detect Bax (Active Monomer) in samples from 人, 小鼠 和 大鼠. It has been validated for IHC, IP 和 WB.
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产品编号 ABIN7072202
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Recombinant Bax (Active Monomer) (AA 12-24), (AA 3-16) 抗体 (ABIN7072202)
抗原
Bax (Active Monomer)
抗体类型
Recombinant Antibody
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
Chimeric
标记
非结合性
应用范围
Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
克隆位点
6A7
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抗原表位
- AA 3-16, AA 12-24
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原理
- Anti-Bax (active monomer) [6A7], Rabbit IgG, kappa
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特异性
- In the presence of nonionic detergent, the antibody avidly binds the monomeric form of Bax, but not Bax complexed with either Bcl-XL or Bcl-2. [6A7 ] Bax antibody only recognizes conformationally changed active Bax.
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交叉反应
- 小鼠, 大鼠
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- KLH conjugated to peptides corresponding to amino acids 3-16 of murine Bax (CGSGEQLGSGGPTSS), amino acids 3-16 of human Bax (CGSGEQPRGGGPTSS), and amino acids 12-24 shared by Bax from both species (CGPTSSEQIMKTGA).
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亚型
- IgG kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Bax (Active Monomer)
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背景
- Bcl-2-like protein 4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4
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UniProt
- Q07812
抗原
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