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Recombinant Bax (Active Monomer) (AA 12-24), (AA 3-16) 抗体

This 小鼠 单克隆 antibody specifically detects Bax (Active Monomer) in IHC, IP 和 WB. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7072201
发货至: 中国
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Quick Overview for Recombinant Bax (Active Monomer) (AA 12-24), (AA 3-16) 抗体 (ABIN7072201)

抗原

Bax (Active Monomer)

抗体类型

Recombinant Antibody

适用

人, 小鼠, 大鼠

宿主

  • 1
小鼠

克隆类型

  • 1
单克隆

标记

  • 1
非结合性

应用范围

Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)

克隆位点

6A7
  • 抗原表位

    AA 3-16, AA 12-24

    原理

    Anti-Bax (active monomer) [6A7], Mouse IgG1, kappa

    特异性

    In the presence of nonionic detergent, the antibody avidly binds the monomeric form of Bax, but not Bax complexed with either Bcl-XL or Bcl-2. [6A7 ] Bax antibody only recognizes conformationally changed active Bax.

    交叉反应

    小鼠, 大鼠

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    纯化方法

    Protein A affinity purified

    免疫原

    KLH conjugated to peptides corresponding to amino acids 3-16 of murine Bax (CGSGEQLGSGGPTSS), amino acids 3-16 of human Bax (CGSGEQPRGGGPTSS), and amino acids 12-24 shared by Bax from both species (CGPTSSEQIMKTGA).

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    Bax (Active Monomer)

    背景

    Bcl-2-like protein 4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4

    UniProt

    Q07812
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