VIPR1 抗体 (Extracellular)
Quick Overview for VIPR1 抗体 (Extracellular) (ABIN7043875)
抗原
See all VIPR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 52-65, Extracellular
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原理
- A Rabbit Polyclonal Antibody to VPAC1 Receptor
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特异性
- Extracellular, N-terminus
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Human - 13,14 amino acid residues identical, rat,mouse - 12
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产品特性
- Anti-VPAC1 (VIPR1) (extracellular) Antibody (ABIN7043875, ABIN7045329 and ABIN7045330) is a highly specific antibody directed against an epitope of human VIP and PACAP receptor 1. The antibody can be used in western blot, immunohistochemistry, immunocytochemistry, live cell imaging, and indirect flow cytometry applications. It has been designed to recognize VPAC1 from mouse, rat, and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)EEAQLENETIG(S)SK, corresponding to amino acid residues 52-65 of human VPAC1
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亚型
- IgG
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anti-Vasoactive Intestinal Peptide Receptor 1 (VIPR1) (AA 351-457) antibody
VIPR1 适用: 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Vasoactive Intestinal Peptide Receptor 1 (VIPR1) (AA 305-334), (C-Term) antibodyVIPR1 适用: 人 WB 宿主: 兔 Polyclonal RB40946 unconjugated
anti-Vasoactive Intestinal Peptide Receptor 1 (VIPR1) (Cytoplasmic Domain) antibodyVIPR1 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Vasoactive Intestinal Peptide Receptor 1 (VIPR1) (Cytoplasmic Domain) antibodyVIPR1 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Vasoactive Intestinal Peptide Receptor 1 (VIPR1) (Internal Region) antibodyVIPR1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vasoactive Intestinal Peptide Receptor 1 (VIPR1) (Internal Region) antibodyVIPR1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vasoactive Intestinal Peptide Receptor 1 (VIPR1) antibodyVIPR1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vasoactive Intestinal Peptide Receptor 1 (VIPR1) (Internal Region) antibodyVerified VIPR1 适用: 大鼠, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Vasoactive Intestinal Peptide Receptor 1 (VIPR1) (AA 1-457) antibodyVIPR1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Vasoactive Intestinal Peptide Receptor 1 (VIPR1) (AA 1-457) antibodyVIPR1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100
Application Dilutions Western blot wb: 1:400
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说明
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Cited Application: IFC
Negative Control: (ABIN7237555)
Blocking Peptide: (ABIN7237555)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- VIPR1 (Vasoactive Intestinal Peptide Receptor 1 (VIPR1))
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别名
- VIPR1
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背景
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VIP and PACAP receptor 1, Vasoactive intestinal polypeptide receptor 1, Pituitary adenylate cyclase-activating polypeptide type II receptor, PACAP type II receptor, PACAP-R2,Vasointestinal peptide (VIP) and pituitary adenylate cyclase-activating peptide (PACAP) belong to the glucagon hormone superfamily, which includes secretin, growth hormone-releasing hormone (GHRH), glucagon, glucagon-like peptides 1 and 2 (GLP-1 and GLP-2), peptide histidine methionine (PHM), and glucose-dependent insulinotropic polypeptide (GIP)1. PACAP and VIP effects have been described in the digestive tract, cardiovascular system, airways, reproductive system, immune system, endocrine glands, and brain2. VIP and PACAP share a common G-protein coupled receptor, VPAC13.VPAC1 is a membrane-associated protein and shares significant homology with members of the G-protein coupled class B receptor family, the most important of which is the presence of large N-terminal extracellular domains which contain 10 highly conserved amino acids including six cysteines, putative N-terminal leader sequences and several potential N-glycosylation sites4. In the CNS, VPAC1 receptors are abundantly localized in piriform cortex, cerebral cortex, suprachiasmatic nucleus, hippocampus, and pineal gland5. In peripheral tissues, VPAC1 receptors have been found in breast, kidney, liver, lung, prostate, spleen, and mucosa of the gastrointestinal tract6. VPAC1 mediates a large array of VIP and PACAP actions on exocrine secretion, hormones release, muscle relaxation, metabolism, fetus growth, tumor cells and embryonic brain development7.
Alternative names: VPAC1 (VIPR1), VIP and PACAP receptor 1, Vasoactive intestinal polypeptide receptor 1, Pituitary adenylate cyclase-activating polypeptide type II receptor, PACAP type II receptor, PACAP-R2 -
基因ID
- 7433
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NCBI登录号
- NM_004624
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UniProt
- P32241
抗原
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