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VIPR1 抗体 (Extracellular)

VIPR1 适用: 人 WB, IHC, IF, IF (cc), LCI, IC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7043875
发货至: 中国
  • 抗原 See all VIPR1 抗体
    VIPR1 (Vasoactive Intestinal Peptide Receptor 1 (VIPR1))
    抗原表位
    • 15
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 52-65, Extracellular
    适用
    • 38
    • 24
    • 24
    • 2
    • 2
    • 1
    • 1
    宿主
    • 52
    • 3
    • 1
    克隆类型
    • 55
    • 1
    多克隆
    标记
    • 29
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VIPR1 antibody is un-conjugated
    应用范围
    • 42
    • 21
    • 13
    • 13
    • 9
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunofluorescence (Cultured Cells) (IF (cc)), Live Cell Imaging (LCI), Immunochromatography (IC)
    原理
    A Rabbit Polyclonal Antibody to VPAC1 Receptor
    特异性
    Extracellular, N-terminus
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Human - 13,14 amino acid residues identical, rat,mouse - 12
    产品特性
    Anti-VPAC1 (VIPR1) (extracellular) Antibody (ABIN7043875, ABIN7045329 and ABIN7045330)) is a highly specific antibody directed against an epitope of human VIP and PACAP receptor 1. The antibody can be used in western blot, immunohistochemistry, immunocytochemistry, live cell imaging, and indirect flow cytometry applications. It has been designed to recognize VPAC1 from mouse, rat, and human samples.
    纯化方法
    Affinity purified on immobilized antigen.
    免疫原

    Immunogen: Synthetic peptide

    Immunogen Sequence: (C)EEAQLENETIG(S)SK, corresponding to amino acid residues 52-65 of human VPAC1

    亚型
    IgG
    Top Product
    Discover our top product VIPR1 Primary Antibody
  • 应用备注

    Antigen preadsorption control: 1 μg peptide per 1 μg antibody

    Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100

    Application Dilutions Western blot wb: 1:400

    说明

    Cited Application: IFC

    Negative Control: BLP-VR001

    Blocking Peptide: BLP-VR001

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4
    储存条件
    4 °C,-20 °C
    储存方法

    Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

    Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

  • 抗原
    VIPR1 (Vasoactive Intestinal Peptide Receptor 1 (VIPR1))
    别名
    VIPR1 (VIPR1 产品)
    背景
    VIP and PACAP receptor 1, Vasoactive intestinal polypeptide receptor 1, Pituitary adenylate cyclase-activating polypeptide type II receptor, PACAP type II receptor, PACAP-R2,Vasointestinal peptide (VIP) and pituitary adenylate cyclase-activating peptide (PACAP) belong to the glucagon hormone superfamily, which includes secretin, growth hormone-releasing hormone (GHRH), glucagon, glucagon-like peptides 1 and 2 (GLP-1 and GLP-2), peptide histidine methionine (PHM), and glucose-dependent insulinotropic polypeptide (GIP)1. PACAP and VIP effects have been described in the digestive tract, cardiovascular system, airways, reproductive system, immune system, endocrine glands, and brain2. VIP and PACAP share a common G-protein coupled receptor, VPAC13.VPAC1 is a membrane-associated protein and shares significant homology with members of the G-protein coupled class B receptor family, the most important of which is the presence of large N-terminal extracellular domains which contain 10 highly conserved amino acids including six cysteines, putative N-terminal leader sequences and several potential N-glycosylation sites4. In the CNS, VPAC1 receptors are abundantly localized in piriform cortex, cerebral cortex, suprachiasmatic nucleus, hippocampus, and pineal gland5. In peripheral tissues, VPAC1 receptors have been found in breast, kidney, liver, lung, prostate, spleen, and mucosa of the gastrointestinal tract6. VPAC1 mediates a large array of VIP and PACAP actions on exocrine secretion, hormones release, muscle relaxation, metabolism, fetus growth, tumor cells and embryonic brain development7.

    Alternative names: VPAC1 (VIPR1), VIP and PACAP receptor 1, Vasoactive intestinal polypeptide receptor 1, Pituitary adenylate cyclase-activating polypeptide type II receptor, PACAP type II receptor, PACAP-R2
    基因ID
    7433
    NCBI登录号
    NM_004624
    UniProt
    P32241
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