TRPV1 抗体 (C616S, Extracellular)
Quick Overview for TRPV1 抗体 (C616S, Extracellular) (ABIN7043838)
抗原
See all TRPV1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 605-619, C616S, Extracellular
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原理
- A Rabbit Polyclonal Antibody to Rat TRPV1 (VR1) Channel
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特异性
- 3rd extracellular loop
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预测反应
- Rat - 14 out of 15 amino acid residues identical Mouse - 12 out of 15 amino acid residues identicalWon't recognize TRPV1 from human samples
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产品特性
- Anti-Rat TRPV1 (VR1) (extracellular) Antibody (ABIN7043838, ABIN7043986 and ABIN7043987) is a highly specific antibody directed against an extracellular epitope of the rat TRPV1 channel. The antibody can be used in western blot, immunohistochemistry, and live cell imaging applications. It has been designed to recognize TRPV1 from rat samples only.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)NSLPMESTPHK*SRGS, corresponding to amino acid residues 605-619 of rat TRPV1 with replacement of cysteine 616 (C616) with serine (*S)
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亚型
- IgG
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anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) (AA 21-124) antibody
TRPV1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F5 unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) (AA 21-124) antibodyTRPV1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A8 unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) (AA 124-153), (N-Term) antibodyTRPV1 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB33721 unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) antibodyTRPV1 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) (AA 824-838), (Intracellular) antibodyKO Validated TRPV1 适用: 大鼠 WB, IHC, IF, FACS, IC 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) (AA 1-155) antibodyTRPV1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) (AA 605-619), (C616S), (Extracellular) antibody (Atto 488)TRPV1 适用: 大鼠 IHC, IF, FACS, LCI, IC 宿主: 兔 Polyclonal Atto 488
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) (AA 1-153) antibodyTRPV1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) (C-Term) antibodyTRPV1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) (AA 21-124) antibodyTRPV1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100
Application Dilutions Western blot wb: 1:200
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- TRPV1 (Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1))
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别名
- TRPV1
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背景
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Transient receptor potential cation channel subfamily V member 1, Capsaicin receptor, Vanilloid receptor 1, OTRPC1,TRP channels are a large family (about 28 genes) of plasma membrane, non-selective cationic channels that are either specifically or ubiquitously expressed in excitable and non-excitable cells.1According to IUPHAR the TRP family comprises of three main subfamilies on the basis of sequence homology, TRPC, TRPM and TRPV (to date, three extra subfamilies are considered to belong to the TRP family, the TRPA, TRPML, and TRPP).1-4 The TRPV subfamily consists of six members, TRPV1-6.5TRPV1 channel has many activators among them heat, protons, vanilloids like capsaicin, reiniferatoxin (RTX), and lipids. This channel is associated with tissue injury and inflammation.6,7TRPV1 is expressed predominantly in nociceptors and in sensory neurons.Recent studies demonstrated involvement of TRPV1 in apoptosis where inhibition of the receptor prevented apoptosis.8,9
Alternative names: TRPV1 (VR1), Transient receptor potential cation channel subfamily V member 1, Capsaicin receptor, Vanilloid receptor 1, OTRPC1 -
基因ID
- 83810
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NCBI登录号
- NM_018727
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UniProt
- O35433
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途径
- Dicarboxylic Acid Transport
抗原
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