TRPM6 抗体 (Extracellular)
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Quick Overview for TRPM6 抗体 (Extracellular) (ABIN7043835)
抗原
See all TRPM6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 802-815, Extracellular
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原理
- A Rabbit Polyclonal Antibody to TRPM6 Channel
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特异性
- 1st extracellular loop
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交叉反应
- 小鼠, 大鼠
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预测反应
- 14 amino acid residues identical,Rat - 13, human - 11
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产品特性
- Anti-TRPM6 (extracellular) Antibody (ABIN7043835, ABIN7044012 and ABIN7044013) is a highly specific antibody directed against an epitope of the mouse protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize TRPM6 from mouse, rat, and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: CVKDYDLERGPDEK, corresponding to amino acid residues 802-815 of mouse TRPM6
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亚型
- IgG
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200
Application Dilutions Western blot wb: 1:200
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说明
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Cited Application: IP|IHC|ICC
Negative Control: (ABIN7237463)
Blocking Peptide: (ABIN7237463)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- TRPM6 (Transient Receptor Potential Cation Channel, Subfamily M, Member 6 (TRPM6))
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别名
- TRPM6
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背景
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Transient receptor potential cation channel subfamily M member 6, Channel kinase 2, CHAK2, Melastatin-related TRP cation channel 6,TRP channels are a large family (about 28 genes) of plasma membrane, non-selective cationic channels that are either specifically or ubiquitously expressed in excitable and non-excitable cells.1 The TRP channels have putative six-transmembrane domains (TM) with a pore domain between the fifth and the six TM, and all assemble as tetramers. Both the N- and the C-terminus of all TRPs are intracellular.3According to IUPHAR the TRP family comprises of three main subfamilies on the basis of sequence homology, TRPC (canonical), TRPV (vanilloid) and TRPM (melastatin). To date, three extra subfamilies are also considered to belong to the TRP family, the TRPA, TRPML, and the TRPP.1-4The TRPM subfamily consists of eight members, TRPM1 to TRPM8, which also can be further subdivided into four subgroups based on their sequence homology: (1)TRPM1 and TRPM3 (2) TRPM6 and TRPM7 (3) TRPM4 and TRPM5 (4) TRPM2 and TRPM8.5
Alternative names: TRPM6, Transient receptor potential cation channel subfamily M member 6, Channel kinase 2, CHAK2, Melastatin-related TRP cation channel 6 -
基因ID
- 225997
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NCBI登录号
- NM_017662
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UniProt
- Q8CIR4
抗原
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