SNCG 抗体 (AA 96-108)
Quick Overview for SNCG 抗体 (AA 96-108) (ABIN7043802)
抗原
See all SNCG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 96-108
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原理
- A Rabbit Polyclonal Antibody to Gamma-Synuclein
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特异性
- C-terminus
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交叉反应
- 小鼠, 大鼠
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交叉反应 （详细）
- Not recommended for use with human samples.
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预测反应
- Mouse - identical
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产品特性
- Anti-Gamma-Synuclein Antibody (ABIN7043802, ABIN7045184 and ABIN7045185) is a highly specific antibody directed against an epitope of the rat protein. It can be used in western blot analysis. It has been designed to recognize γ-Synuclein from mouse and rat samples. The antibody will not recognize the protein from human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)RKEDLEPPAQDQE, corresponding to amino acid residues 96 - 108 of rat gamma-Synuclein
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亚型
- IgG
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anti-Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG) (AA 1-121) antibody
SNCG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG) (AA 1-123) antibodySNCG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG) (C-Term) antibodySNCG 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG) (AA 1-127) antibodySNCG 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG) antibodySNCG 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG) (AA 21-127) antibodySNCG 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C3 unconjugated
anti-Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG) antibodySNCG 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 1H10D2 unconjugated
anti-Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG) (AA 1-127) antibodySNCG 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG) (AA 2-123) antibodySNCG 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG) (C-Term) antibodySNCG 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200
Application Dilutions Western blot wb: 1:200
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说明
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Negative Control: (ABIN7237365)
Blocking Peptide: (ABIN7237365)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- SNCG (Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG))
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别名
- SNCG
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背景
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γ-Synuclein, Breast Cancer-Specific Gene 1 Protein, BCSG1, Persyn, Synoretin, SNCG,γ-synuclein is a 127 amino acids protein that belongs to the synuclein family of proteins. Synucleins are natively unfolded proteins, i.e. they have no secondary or tertiary structure in solution and hence these proteins are heat stable. The unusual biophysical properties of synucleins are rooted in their characteristic primary sequence that includes a highly conserved N-terminal domain with an 11- residue repeat and a less conserved acidic C-terminal domain that contains many proline residues1.Mammalian γ-synuclein, encoded by BCSG1 (breast cancer specific gene 1), was discovered in a screen for breast cancer markers2. It is expressed in the peripheral nervous system in primary sensory neurons, sympathetic neurons, and motor neurons. It is also detected in the brain3, olfactory epithelium and breast/ovarian tumors4. Indeed, exogenous expression of this protein increases the invasive and metastatic potential of breast tumors5.The roles of synucleins are not fully elucidated but this group of conserved and unusual proteins contributes to diverse disease processes spanning neurodegenerative disease and cancer and hence, studying the synucleins specific cellular activity is very tempting and promising.
Alternative names: γ-Synuclein, Breast Cancer-Specific Gene 1 Protein, BCSG1, Persyn, Synoretin, SNCG -
基因ID
- 64347
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NCBI登录号
- NM_001330120
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UniProt
- O76070
抗原
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