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STX3 抗体 (Cytosolic, N-Term)

The 兔 多克隆 anti-STX3 antibody is suitable to detect STX3 in samples from 大鼠. It has been validated for WB, IF 和 IC.
产品编号 ABIN7043795
发货至: 中国
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Quick Overview for STX3 抗体 (Cytosolic, N-Term) (ABIN7043795)

抗原

See all STX3 抗体
STX3 (Syntaxin 3 (STX3))

适用

  • 43
  • 27
  • 26
大鼠

宿主

  • 43

克隆类型

  • 24
  • 19
多克隆

标记

  • 15
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This STX3 antibody is un-conjugated

应用范围

  • 21
  • 18
  • 16
  • 15
  • 14
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunochromatography (IC)

质量等级

KO Validated
  • 抗原表位

    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-16, Cytosolic, N-Term

    原理

    A Rabbit Polyclonal Antibody to Syntaxin 3

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Mouse,human - identical

    产品特性

    Anti-Syntaxin 3 Antibody is directed against an epitope of rat Syntaxin 3. Anti-Syntaxin 3 Antibody (ABIN7043795 and ABIN7044652) can be used in western blot and immunocytochemistry applications. It has been designed to recognize Syntaxin 3 from rat, mouse and human samples.

    纯化方法

    Affinity purified on immobilized antigen.

    免疫原

    KDRLEQLKAKQLTQD(C), corresponding to amino acid residues 2-16 of rat syntaxin 3

    亚型

    IgG
  • 应用备注

    WB: 1:200

    FC: The optimal concentration should be determined by the user

    ICC: The optimal concentration should be determined by the user

    IHC: The optimal concentration should be determined by the user

    IP: The optimal concentration should be determined by the user

    说明

    Negative Control: (ABIN7237343)

    Blocking Peptide: (ABIN7237343)

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

    浓度

    0.8 mg/mL

    缓冲液

    PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
  • 抗原

    STX3 (Syntaxin 3 (STX3))

    别名

    STX3

    背景

    Synonyms: STX3

    Description: Syntaxin 3 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein superfamily. The family includes 36 members in humans and is characterized by the SNARE motif, an evolutionarily conserved stretch of 60-70 amino acids that are arranged in heptad repeats1,2. SNARE proteins are involved in exocytosis and intracellular vesicle trafficking and are essential for cell growth, hormone secretion and neurotransmission, processes that require rapid, targeted, and regulated membrane fusion1,2.SNAREs can be roughly divided into vesicular (v-SNAREs) and target (t-SNAREs) based on their distribution on the transport vesicle or target membrane respectively. Thus, assembly of cognate v-/t-SNAREs between two opposing membranes generates trans-SNARE complexes, which bring the lipid bilayers in close proximity and drive membrane fusion.Syntaxin 3, like most SNAREs, is a type IV membrane protein with a relatively large N-terminus containing the SNARE motif located in the cytoplasmic side and a transmembrane domain located close to the C-terminus that functions as an anchor1,2.Syntaxin 3 functions as a plasma membrane protein t-SNARE that is involved in epithelial cell polarization. Indeed, Syntaxin 3 is specifically localized in the apical membrane of polarized epithelial cells where it likely has a role in the polarized trafficking of newly synthesized proteins3.

    基因ID

    81802

    NCBI登录号

    NM_004177

    UniProt

    Q08849

    途径

    Synaptic Vesicle Exocytosis
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