STX3 抗体 (Cytosolic)
Quick Overview for STX3 抗体 (Cytosolic) (ABIN7043795)
抗原
See all STX3 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 2-16, Cytosolic
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原理
- A Rabbit Polyclonal Antibody to Syntaxin 3
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特异性
- Cytoplasmic, N-terminus
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Mouse,human - identical
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产品特性
- Anti-Syntaxin 3 Antibody is directed against an epitope of rat Syntaxin 3. Anti-Syntaxin 3 Antibody (ABIN7043795 and ABIN7044652) can be used in western blot and immunocytochemistry applications. It has been designed to recognize Syntaxin 3 from rat, mouse and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: KDRLEQLKAKQLTQD(C), corresponding to amino acid residues 2-16 of rat syntaxin 3
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亚型
- IgG
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anti-Syntaxin 3 (STX3) (AA 1-263) antibody
STX3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 3 (STX3) antibodySTX3 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 3 (STX3) (AA 178-205) antibodySTX3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB17355 unconjugated
anti-Syntaxin 3 (STX3) (AA 1-214) antibodySTX3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 3 (STX3) (Cytoplasmic Domain) antibodySTX3 适用: 人, 大鼠 WB, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 3 (STX3) (Middle Region) antibodySTX3 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
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说明
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Negative Control: (ABIN7237343)
Blocking Peptide: (ABIN7237343)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- STX3 (Syntaxin 3 (STX3))
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别名
- STX3
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背景
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STX3,Syntaxin 3 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein superfamily. The family includes 36 members in humans and is characterized by the SNARE motif, an evolutionarily conserved stretch of 60-70 amino acids that are arranged in heptad repeats1,2. SNARE proteins are involved in exocytosis and intracellular vesicle trafficking and are essential for cell growth, hormone secretion and neurotransmission, processes that require rapid, targeted, and regulated membrane fusion1,2.SNAREs can be roughly divided into vesicular (v-SNAREs) and target (t-SNAREs) based on their distribution on the transport vesicle or target membrane respectively. Thus, assembly of cognate v-/t-SNAREs between two opposing membranes generates trans-SNARE complexes, which bring the lipid bilayers in close proximity and drive membrane fusion.Syntaxin 3, like most SNAREs, is a type IV membrane protein with a relatively large N-terminus containing the SNARE motif located in the cytoplasmic side and a transmembrane domain located close to the C-terminus that functions as an anchor1,2.Syntaxin 3 functions as a plasma membrane protein t-SNARE that is involved in epithelial cell polarization. Indeed, Syntaxin 3 is specifically localized in the apical membrane of polarized epithelial cells where it likely has a role in the polarized trafficking of newly synthesized proteins3.
Alternative names: Syntaxin 3, STX3 -
基因ID
- 81802
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NCBI登录号
- NM_004177
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UniProt
- Q08849
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途径
- Synaptic Vesicle Exocytosis
抗原
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