STOML2 抗体 (Intracellular)
Quick Overview for STOML2 抗体 (Intracellular) (ABIN7043779)
抗原
See all STOML2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 208-222, Intracellular
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原理
- A Rabbit Polyclonal Antibody to Stomatin-like Protein 2
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特异性
- Intracellular
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Mouse,human - identical
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产品特性
- Anti-STOML2/ Antibody (ABIN7043779, ABIN7044518 and ABIN7044519) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot analysis. It has been designed to recognize Stomatin-like protein 2 from human, rat, and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)EGTRESAINVAEGKK, corresponding to amino acid residues 208-222 of rat Stomatin-like protein 2
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亚型
- IgG
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anti-Stomatin (EPB72)-Like 2 (STOML2) (AA 1-356) antibody
STOML2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Stomatin (EPB72)-Like 2 (STOML2) (AA 1-356) antibodySTOML2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Stomatin (EPB72)-Like 2 (STOML2) (AA 29-356) antibodySTOML2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Stomatin (EPB72)-Like 2 (STOML2) antibodySTOML2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Stomatin (EPB72)-Like 2 (STOML2) (AA 29-356) antibodySTOML2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Stomatin (EPB72)-Like 2 (STOML2) (AA 199-213) antibodySTOML2 适用: 人, 小鼠, 大鼠 WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Stomatin (EPB72)-Like 2 (STOML2) (C-Term) antibodySTOML2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Stomatin (EPB72)-Like 2 (STOML2) (AA 161-189) antibodySTOML2 适用: 人 WB 宿主: 兔 Polyclonal RB42787 unconjugated
anti-Stomatin (EPB72)-Like 2 (STOML2) (C-Term) antibodySTOML2 适用: 人, Cow, 犬, Pig, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:400-1:800
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说明
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Negative Control: (ABIN7237288)
Blocking Peptide: (ABIN7237288)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- STOML2 (Stomatin (EPB72)-Like 2 (STOML2))
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别名
- STOML2
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背景
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Paraprotein target 7, EPB72-like protein 2, Stomatin-like protein 2,Stomatin-like protein 2 (STOML2, SLP-2) is a key protein on the mitochondrial inner membrane and a member of the stomatin superfamily. STOML2 is widely expressed in human tissues such as the brain, lung, and kidneys and interacts with prohibitin-1 and 2. It plays an important role in numerous physiological processes including organizing sphingolipid and cholesterol-rich lipid rafts, regulating ion channel conductance, and linking other integral membrane proteins to the peripheral cytoskeleton1,2.STOML2 shares a consensus stomatin signature sequence that defines the stomatin gene family. However, it lacks a NH2-terminal hydrophobic domain shared by other members3.Studies show that STOML2 expression is upregulated in various human cancer tissues including gastric cancer, endometrial adenocarcinoma, and breast cancer. The protein may play an important role in the incidence and development of tumor and it is suggested that SLP-2 is a potential oncogene. Knockdown of STOML2 protein significantly restrains the viability, migration, and invasion of hepatoma cell line1,2.
Alternative names: STOML2/SLP-2, Paraprotein target 7, EPB72-like protein 2, Stomatin-like protein 2 -
基因ID
- 298203
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NCBI登录号
- NM_013442
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UniProt
- Q4FZT0
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途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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