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SSTR2 抗体 (C-Term, Intracellular)

This 兔 多克隆 antibody specifically detects SSTR2 in WB 和 IHC. It exhibits reactivity toward 大鼠.
产品编号 ABIN7043764
发货至: 中国
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Quick Overview for SSTR2 抗体 (C-Term, Intracellular) (ABIN7043764)

抗原

See all SSTR2 抗体
SSTR2 (Somatostatin Receptor 2 (SSTR2))

适用

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大鼠

宿主

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克隆类型

  • 40
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  • 2
多克隆

标记

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This SSTR2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 339-359, C-Term, Intracellular

    原理

    A Rabbit Polyclonal Antibody to Somatostatin Receptor Type 2

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Mouse,human - identical

    产品特性

    Anti-Somatostatin Receptor Type 2 Antibody (ABIN7043764, ABIN7045263 and ABIN7045264) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize SSTR2 from human, mouse, and rat samples.

    纯化方法

    Affinity purified on immobilized antigen.

    免疫原

    (C)ERSDSKQDKSRLNETTETQRT corresponding to residues 339-359 of rat SSTR2

    亚型

    IgG
  • 应用备注

    WB: 1:400

    FC: The optimal concentration should be determined by the user

    ICC: The optimal concentration should be determined by the user

    IHC: The optimal concentration should be determined by the user

    IP: The optimal concentration should be determined by the user

    说明

    Negative Control: (ABIN7237235)

    Blocking Peptide: (ABIN7237235)

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

    浓度

    0.8 mg/mL

    缓冲液

    PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
  • 抗原

    SSTR2 (Somatostatin Receptor 2 (SSTR2))

    别名

    SSTR2

    背景

    Synonyms: SSTR2a, SS2R, Smstr2, SRIF1A

    Description: Somatostatin is a small cyclic peptide that is widely expressed throughout the central nervous system and peripheral tissues1. In peripheral tissues, somatostatin exerts inhibitory effects on secretion processes, whereas in the brain, it acts as a neurotransmitter in both a stimulatory and an inhibitory manner1,2.Somatostatin mediates its action via six high affinity G-protein coupled receptors (SSTR1, SSTR2a, SSTR2b, SSTR3, SSTR4, and SSTR5), which are encoded by five genes1,2. Expression of the different receptors is developmentally regulated in a time- and tissue-specific manner2.Somatostatin receptors have been found on a variety of neuroendocrine tumors, such as paragangliomas, carcinoids, and breast tumors3. Synthetic peptide derivatives of somatostatin have been successfully used in the treatment of neuroendocrine malignancies and in vivo imaging of tumors that are positive for somatostatin receptors4.In general, SSTR2 is the most common SSTR subtype found in human tumors, followed by SSTR1, with SSTR3 and SSTR4 being less common.

    基因ID

    54305

    NCBI登录号

    NM_001050

    UniProt

    P30680
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